The Winter School “Trends & Development of Motor Neuron Diseases in Africa and Middle East” was organized by Assoc. Prof. Nabila Hamdi in collaboration with UULM and Ain Shams University. It aimed at narrowing the gap between the different countries within Africa/Middle East and Europe by tackling the advances and challenges in motor neuron diseases research and clinical practice. The school gathered clinicians, scientists and students from Egypt, Tunisia, Saudi Arabia, Jordan, and Germany.