Research

2017

Journal 2017

Investigating the link between MCP-1 A-2518G, RANTES G-403A, CX3CR1 V249I and MTHFR C677T gene polymorphisms and the risk of acute myocardial infarction among Egyptians

Ingy M. Hashad, Mohamed F. Abdel Rahman, Natalia Alenina, Michael Bader, Mohamed Z. Gad : Investigating the link between MCP-1 A-2518G, RANTES G-403A, CX3CR1 V249I and MTHFR C677T gene polymorphisms and the risk of acute myocardial infarction among Egyptians , Meta Gene , 2017.
11: 181 -188

Journal 2017

"Desert" gene (Chr9p21) variants as novel markers for coronary artery disease

Heba A. Shendy, Sally I. Hassanein, Mohamed Z. Gad : "Desert" gene (Chr9p21) variants as novel markers for coronary artery disease, Anatol J Cardiol. , 2017.
[Epub ahead of print]

Journal 2017

A chiral enantioseparation generic strategy for anti-Alzheimer and antifungal drugs by short end injection capillary electrophoresis using an experimental design approach.

Ahmed M. Abdel-Megied, Rasha S. Hanafi, Hassan Y. Aboul-Enein : A chiral enantioseparation generic strategy for anti-Alzheimer and antifungal drugs by short end injection capillary electrophoresis using an experimental design approach., Chirality, DOI: 10.1002/chir.22777 , 2017.

Journal 2017

Computer-Assisted HPLC Method Development Using DryLab® for Determination of Major Phenolic Components in Corchorus olitorius and Vitis vinifera by using HPLC-PDA-ESI-qTOF-MSn

Heba Handoussa, Rasha Hanafi, Ahmed El-Khatib, Michael Linscheid, Laila Mahran and Nahla Ayoub. : Computer-Assisted HPLC Method Development Using DryLab® for Determination of Major Phenolic Components in Corchorus olitorius and Vitis vinifera by using HPLC-PDA-ESI-qTOF-MSn, Journal of Botanical Sciences , 2017.
Journal of Botanical Sciences, 6 (1): 9-16 (2017)

Journal 2017

Computer-Assisted HPLC Method Development Using DryLab® for Determination of Major Phenolic Components in Corchorus olitorius and Vitis vinifera by using HPLC-PDA-ESI-qTOF-MSn

Heba Handoussa, Rasha Hanafi, Ahmed El-Khatib, Michael Linscheid, Laila Mahran and Nahla Ayoub : Computer-Assisted HPLC Method Development Using DryLab® for Determination of Major Phenolic Components in Corchorus olitorius and Vitis vinifera by using HPLC-PDA-ESI-qTOF-MSn, Research & Reviews: Journal of Botanical Sciences , 2017.

Journal 2017

Destabilizing the interplay between miR-1275 and IGF2BPs by Tamarix articulata and quercetin in hepatocellular carcinoma

Yasmin Shaalan, Heba Handoussa, Rana Youness, Reem A. Assal, Ahmed H. El- Khatib, Michael Linscheid, Hend M. El Tayebi, Ahmed I. Abdelaziz : Destabilizing the interplay between miR-1275 and IGF2BPs by Tamarix articulata and quercetin in hepatocellular carcinoma, Journal of Natural Product Research , 2017.

Book 2017

Determination of Mercaptopurine metabolites and toxicity in children

Rasha Hanafi, Eman Abdelsayed, Iman Sidhom, Mohamed Gad, Sahar Abdelmaksoud : Determination of Mercaptopurine metabolites and toxicity in children, Scholars' Press , 2017.

Book 2017

Determination of Mercaptopurine metabolites and toxicity in children

Rasha Hanafi, Iman Sidhom, Eman Abdel-Sayed, Sahar Abdel-Maksoud, Mohamed Gad : Determination of Mercaptopurine metabolites and toxicity in children , Scholars' Press , 2017.
ISBN-10: 6202300094 ISBN-13: 978-6202300094

Journal 2017

HPLC Determination of the Levels of 6-Mercaptopurine Metabolites Suitable for the Clinical Risk Assessment of its Toxicity among Egyptian Children with Acute Lymphocytic Leukemia

Gad - HPLC Determination of 6-MP.pdf Eman Abdelsayed, Sahar Abdel- Maksoud , Iman Sidhom, Mohamed Gad and Rasha Hanafi : HPLC Determination of the Levels of 6-Mercaptopurine Metabolites Suitable for the Clinical Risk Assessment of its Toxicity among Egyptian Children with Acute Lymphocytic Leukemia, Journal of Analytical & Bioanalytical Techniques , 2017.
8: 358. doi: 10.4172/2155-9872.1000358

Journal 2017

HPLC Determination of the Levels of 6-Mercaptopurine Metabolites Suitable for the Clinical Risk Assessment of its Toxicity among Egyptian Children with Acute Lymphocytic Leukemia

Anal Bioanal Tech 2017, 8,2.pdf Eman Abdelsayed, Sahar Maksoud, Iman Sidhom, Mohamed Gad and Rasha Hanafi : HPLC Determination of the Levels of 6-Mercaptopurine Metabolites Suitable for the Clinical Risk Assessment of its Toxicity among Egyptian Children with Acute Lymphocytic Leukemia, Journal of Analytical & Bioanalytical Techniques , 2017.
2017, 8:2 DOI: 10.4172/2155-9872.1000358

Journal 2017

HPLC Determination of the Levels of 6-Mercaptopurine Metabolites Suitable for the Clinical Risk Assessment of its Toxicity among Egyptian Children with Acute Lymphocytic Leukemia

Eman A. Abdelsayed, Sahar A. Maksoud, Iman Sidhom, Mohamed Z Gad, Rasha S. Hanafi : HPLC Determination of the Levels of 6-Mercaptopurine Metabolites Suitable for the Clinical Risk Assessment of its Toxicity among Egyptian Children with Acute Lymphocytic Leukemia, Journal of Analytical & Bioanalytical Techniques , 2017.
8:358

Journal 2017

Independent assortment of GC gene polymorphism (rs2282679) and 25-hydroxyvitamin D levels in Coronary Artery Disease

Nada .K. Sedky, Sally I. Hassanein, Mohamed Gad : Independent assortment of GC gene polymorphism (rs2282679) and 25-hydroxyvitamin D levels in Coronary Artery Disease, Canadian Journal of Physiology and Pharmacology , 2017.
Sep 2017 [Epub ahead of print]

Conference 2017

Independent control of nanoparticle clusters

M. Alaa, A. Klingner, N. Hamdi, S. Abdennadher, and I. S. M. Khalil : Independent control of nanoparticle clusters, International Conference on Manipulation, Manufacturing and Measurement on the Nanoscale (3M Nano), Shanghai, China , 2017.
Best Student Conference Paper Award

Journal 2017

Perturbation of IGF2BP1 transcriptome upon the interplay between miR-486-5p and let-7a.

Mourad HA, Assal RA , Youness RA, El-Tayebi HM, Abdelaziz AI. : Perturbation of IGF2BP1 transcriptome upon the interplay between miR-486-5p and let-7a., Journal of gastroenterology, pancreatology and liver disorders , 2017.

Journal 2017

Polymorphisms in gap junction proteins and their role in predisposition of acute myocardial infarction in Egyptians

Fadwa A El Tahry, Ingy Mostafa, Mohamed Rahman, Mohamed Gad : Polymorphisms in gap junction proteins and their role in predisposition of acute myocardial infarction in Egyptians, Current pharmaceutical biotechnology , 2017.
Oct 2017, 18, 662-668

Journal 2017

Reduction of CD19 Autoimmunity Marker on B cells of Pediatric SLE Patients through Repressing PU.1/TNF-a/BAFF axis Pathway by miR-155

Aboelenein H.R., Hamza M.T., Marzouk H., Youness R.A., Rahmoon M.A., Salah. S., Abdelaziz A.I. : Reduction of CD19 Autoimmunity Marker on B cells of Pediatric SLE Patients through Repressing PU.1/TNF-a/BAFF axis Pathway by miR-155, Growth Factors , 2017.

Journal 2017

Rubbing Against Blood Clots using Helical Robots: Modeling and In Vitro Experimental Validation

Islam S.M. Khalil, Ahmet Fatih Tabak, Khaled Sadek, Dalia Mahdy, Nabila Hamdi, Metin Sitti : Rubbing Against Blood Clots using Helical Robots: Modeling and In Vitro Experimental Validation, IEEE Robotics and Automation Letters , 2017.
Accepted

Conference 2017

Rubbing Against Blood Clots using Helical Robots: Modeling and In Vitro Experimental Validation

Islam S.M. Khalil, Ahmet Fatih Tabak, Khaled Sadek, Dalia Mahdy, Nabila Hamdi, Metin Sitti : Rubbing Against Blood Clots using Helical Robots: Modeling and In Vitro Experimental Validation, IEEE International Conference on Robotics and Automation , 2017.
May 29 - June 3, 2017, Marina Bay Sands Convention Centre, Singapore

Journal 2017

T-786C variation in the promoter sequence of human eNOS gene markedly influences its expression level

Elakkad AM, Abou-Aisha K, Hassanein SI, Gad MZ : T-786C variation in the promoter sequence of human eNOS gene markedly influences its expression level, Drug Discov Ther , 2017.
11(4):193-197. doi: 10.5582/ddt.2016.01083. PMID: 28867751

Journal 2017

The p7 viroporin of the hepatitis C virus contributes to liver inflammation by stimulating production of Interleukin-1ß

2017 Farag p7 stimulates IL-1b BBA Mol Dis.pdf N.S. Farag, U. Breitinger, M. El-Azizi, H.-G. Breitinger : The p7 viroporin of the hepatitis C virus contributes to liver inflammation by stimulating production of Interleukin-1ß, Biochimic at Biohysica Acta - Molecular Basis of Disease , 2017.
IF 4.4

Book Chapter 2017

The Role of Nitric Oxide from Neurological Disease to Cancer.

Maher A, Abdel Rahman MF, Gad MZ. : The Role of Nitric Oxide from Neurological Disease to Cancer., Adv Exp Med Biol. , 2017.
1007:71-88. doi: 10.1007/978-3-319-60733-7_5. MID: 28840553

2016

Conference 2016

The in vivo triad behind the neuromodulatory effect of Bauhinia variegata L

Alaa Selim, Heba Handoussa and Nesrine El-Sayed : The in vivo triad behind the neuromodulatory effect of Bauhinia variegata L, 5th International Conference on Alzheimer’s Disease & Dementia September 29-October 01, 2016 London, UK , 2016.

Journal 2016

. Structure-based design of novel tetrahydro-beta-carboline derivatives with a hydrophilic side chain as potential phosphodiesterase inhibitors.

Ahmed K. Elhady, Sara C. Sigler, Nazih Noureldin, Joshua C. Canzoneri, Nermin S. Ahmed, Gary A. Piazza, Ashraf H. Abadi : . Structure-based design of novel tetrahydro-beta-carboline derivatives with a hydrophilic side chain as potential phosphodiesterase inhibitors., Sci Pharm , 2016.
in press. doi:10.3797/scipharm.1507-16

Journal 2016

. Structure-based design of novel tetrahydro-beta-carboline derivatives with a hydrophilic side chain as potential phosphodiesterase inhibitors.

Ahmed K. Elhady, Sara C. Sigler, Nazih Noureldin, Joshua C. Canzoneri, Nermin S. Ahmed, Gary A. Piazza, Ashraf H. Abadi : . Structure-based design of novel tetrahydro-beta-carboline derivatives with a hydrophilic side chain as potential phosphodiesterase inhibitors., Sci Pharm , 2016.
in press. doi:10.3797/scipharm.1507-16

Journal 2016

A Comparative Metabolomics Approach Reveals Early Biomarkers for Metabolic Response to Acute Myocardial Infarction

Sara Ali, Mohamed Farag, Paul Holvoet, Rasha Sayed Hanafi, Mohamed Zakaria Gad : A Comparative Metabolomics Approach Reveals Early Biomarkers for Metabolic Response to Acute Myocardial Infarction , Scientifc Reports, Nature , 2016.
Scientific Reports 6, Article number: 36359 (2016) doi:10.1038/srep36359

Journal 2016

A Comparative Metabolomics Approach Reveals Early Biomarkers for Metabolic Response to Acute Myocardial Infarction.

Ali SE, Farag MA, Holvoet P, Hanafi RS, Gad MZ : A Comparative Metabolomics Approach Reveals Early Biomarkers for Metabolic Response to Acute Myocardial Infarction., Scientific Reports by Nature publishing , 2016.
2016 Nov 8;6:36359. doi: 10.1038/srep36359. PMID: 27821850

Conference 2016

Approaches to Computer-Aided Drug Design and Drug Re-positioning

Ashraf. H. Abadi. : Approaches to Computer-Aided Drug Design and Drug Re-positioning, Arab-African Pharma Conference, Cairo,Egypt 5-7 May 2016. , 2016.
Keynote Speaker

Journal 2016

Assessment of the Link between Endothelin K198N SNP, Endothelin Concentration and Acute Myocardial Infarction in Egyptians.

Abdel Rahman MF, Hashad IM, Abou-Aisha K, Abdel Maksoud SM, Gad MZ. : Assessment of the Link between Endothelin K198N SNP, Endothelin Concentration and Acute Myocardial Infarction in Egyptians., Clin Exp Pharmacol Physiol , 2016.
2016 Oct 19. doi: 10.1111/1440-1681.12684. [Epub ahead of print] PMID: 27761928

Journal 2016

Augmentation of glycine receptor alpha3 currents suggests a mechanism for glucose-mediated analgesia

2016 GlyR a3 modulation by glucose.pdf Breitinger U, Breitinger HG. (2015) : Augmentation of glycine receptor alpha3 currents suggests a mechanism for glucose-mediated analgesia, Neuroscience Letters , 2016.
Neuroscience Letters 2015 Dec 2. pii: S0304-3940(15)30289-5. doi: 10.1016/j.neulet.2015.11.051. [Epub ahead of print]

Conference 2016

Clinical Pharmacy Session

Ashraf H. Abadi : Clinical Pharmacy Session, Breast Gynecological International Cancer Conference, Clinical Pharmacy , 2016.
Chairperson

Journal 2016

Contradicting Interplay between Insulin-Like Growth Factor-1 and miR-486-5p in Primary NK cells and Hepatoma Cell Lines with a Contemporary Inhibitory Impact on HCC Tumor Progression.

Rana A. Youness, Mai A. Rahmoon, Reem A. Assal, Asmaa Gomaa, Imam Waked, Hend M. El Tayebi, Ahmed I. Abdelaziz. : Contradicting Interplay between Insulin-Like Growth Factor-1 and miR-486-5p in Primary NK cells and Hepatoma Cell Lines with a Contemporary Inhibitory Impact on HCC Tumor Progression., Growth Factors, June 2016 , 2016.

Conference 2016

Corchorus olitorius L. and Origanum majorana L.: Potential Source of High-Value Components for Protection against Neuroinflammation

Reham Wagdy, Reham Abdelkader, Ahmed El-Khatib, Nabila Hamdi, Heba Handoussa : Corchorus olitorius L. and Origanum majorana L.: Potential Source of High-Value Components for Protection against Neuroinflammation, 9th Joint Natural Products Conference 2016, Juy 24-27, Copenhagen, Denmark , 2016.

Journal 2016

Design and synthesis of novel flexible ester-containing analogs of tamoxifen and their evaluation as anticancer agents

Elghazawy, Engel, Hartmann, Hamed, Ahmed & Abadi : Design and synthesis of novel flexible ester-containing analogs of tamoxifen and their evaluation as anticancer agents, Future Medicinal Chemistry , 2016.

Journal 2016

Design and Synthesis of Novel Flexible Ester-containing Analogues of Tamoxifen and Their Evaluation as Anticancer Agents.

Nehal H. Elghazawy, Mathias Engel Rolf W. Hartmann, Mostafa M. Hamed, Nermin S. Ahmed, Ashraf H. Abadi : Design and Synthesis of Novel Flexible Ester-containing Analogues of Tamoxifen and Their Evaluation as Anticancer Agents., Future Medicinal Chemistry , 2016.
8(3), 249-56 (2016)

Conference 2016

Design and Synthesis of Novel Non CYP 2D6 mediated Tamoxifen Analogues

Nehal H. Elghazawy, Nermin S. Ahmed, Bianca Liederer, Rolf Hartmann, Ashraf H. Abadi : Design and Synthesis of Novel Non CYP 2D6 mediated Tamoxifen Analogues , Pharmaceutica 2016 , 2016.

Conference 2016

Design and Synthesis of Novel Non CYP 2D6 mediated Tamoxifen Analogues.

Nehal H. Elghazawy, Nermin S. Ahmed, Bianca Liederer, Rolf Hartmann, Ashraf. H. Abadi. : Design and Synthesis of Novel Non CYP 2D6 mediated Tamoxifen Analogues. , Pharmaceutics & Novel Drug Delivery Systems. March 07-09, 2016 Madrid, Spain. , 2016.
Poster presentation. best poster award

Conference 2016

Design and Synthesis of Novel Tamoxifen Analogues and tehir Evaluation as Sepective Estrogen Receptor Modulators

Ashraf. H. Abadi, Nermin S. Ahmed, Rasha M. Rashied, G?nter Vollmer, Jannette Wober. : Design and Synthesis of Novel Tamoxifen Analogues and tehir Evaluation as Sepective Estrogen Receptor Modulators, Faculty of Pharmacy, Cairo University, 7th International Scientific Conference. , 2016.
, poster presentation. Best Poster Award

Conference 2016

Design and Synthesis of Novel Tamoxifen Analogues and Their Evaluation as Selective Estrogen Receptor Modulators . 7th International Scientific Conference of Faculty of Pharmacy, Cairo ,

Rasha M. Rashied, Nermin S. Ahmed, Jannette Wober, Günter Vollmer, Ashraf H. Abadi : Design and Synthesis of Novel Tamoxifen Analogues and Their Evaluation as Selective Estrogen Receptor Modulators . 7th International Scientific Conference of Faculty of Pharmacy, Cairo ,, 7th International Scientific Conference of Faculty of Pharmacy, Cairo. , 2016.

Journal 2016

Design and synthesis of novel tamoxifen analogues that avoid CYP2D6 metabolism

Ahmed NS, Elghazawy NH, ElHady AK, Engel M, Hartmann RW, Abadi AH. : Design and synthesis of novel tamoxifen analogues that avoid CYP2D6 metabolism, Eur J Med Chem. , 2016.
112:171-9 (2016).

Journal 2016

Design and synthesis of novel tamoxifen analogues that avoid CYP2D6 metabolism

Nermin S. Ahmed , Nehal H. Elghazawy , Ahmed K. ElHady , Matthias Engel , Rolf W. Hartmann , Ashraf H. Abadi : Design and synthesis of novel tamoxifen analogues that avoid CYP2D6 metabolism, European Journal of medicinal Chemistry , 2016.

Conference 2016

Early Elevation of Hydrogen Sulfide (H2S) in Serum of ST Segment Elevation Myocardial Infarction (STEMI) Patients

Sara E. Ali, Mohamed A. Farag, Rasha S. Hanafi, Mohamed Z. Gad (Oral presentation by Prof. Gad) : Early Elevation of Hydrogen Sulfide (H2S) in Serum of ST Segment Elevation Myocardial Infarction (STEMI) Patients, 16th International Union of Biochemistry & Molecular Biology (IUBMB 2016) Conference , 2016.
Vancouver, Canada, July 17-21

Journal 2016

Identification of phenolic secondary metabolites from Schotia brachypetalaSond. (Fabaceae) and demonstration of their antioxidant activities in Caenorhabditis elegans

Mansour Sobeh, Herbenya Peixoto, Rola Labib, Heba Handoussa, Noha Swilam, AhmedEl-Khatib, Michael,W Linscheid, AbdelNasser Singab, Michael Wink, Nahla Ayoub. : Identification of phenolic secondary metabolites from Schotia brachypetalaSond. (Fabaceae) and demonstration of their antioxidant activities in Caenorhabditis elegans, Peer J , 2016.

Conference 2016

In Vitro Validation of Clearing Clogged Vessels using Microrobots

Abdelrahman Hosney, Joseph Abdalla, Ibrahim S. Amin, Nabila Hamdi and Islam S. M. Khalil : In Vitro Validation of Clearing Clogged Vessels using Microrobots, 6th IEEE RAS/EMBS International Conference on Biomedical Robotics and Biomechatronics (BioRob), June 26-29, 2016. UTown, Singapore , 2016.

Journal 2016

Investigation of brain-derived neurotrophic factor (BDNF) gene expression in hypothalamus of obese rats: Modulation by omega-3 fatty acids

Sahar M. Abdel-Maksoud, Sally I. Hassanein, Neveen A. Gohar, Saad M. M. Attia & Mohamed Z. Gad : Investigation of brain-derived neurotrophic factor (BDNF) gene expression in hypothalamus of obese rats: Modulation by omega-3 fatty acids, Nutritional Neuroscience , 2016.
May 1:1-6. [Epub ahead of print]

Conference 2016

Melatonin-Tamoxifen Hybrid Ligand as Potent Agent against Breast Cancer

Zlotos, D.P. Marzouk, M.A.; Hasan, M.; Darveau, T.; Guarinini, L; Browne, E.; Witt-Enderby, P.A. : Melatonin-Tamoxifen Hybrid Ligand as Potent Agent against Breast Cancer , Annual Meeting of the German Pharmaceutical Society, October 2016, Munich , 2016.
Poster presentation

Journal 2016

Metabolites profiling in 18 Saudi date palm fruit cultivars and their antioxidant potential via UPLC-qTOF-MS and multivariate data analyses

Mohammed Farag, Heba Handoussa, Mostafa fekry and Ludger A. Wessjohann. : Metabolites profiling in 18 Saudi date palm fruit cultivars and their antioxidant potential via UPLC-qTOF-MS and multivariate data analyses, Food & Function - Royal Society of Chemistry , 2016.

Conference 2016

miR-155: A Double Faced microRNA With Respect to its impact on Tumorigenesis in Both Natural Killer Cells and Their Target Hepatocytes

Mai A. Rahmoon • Rana A. Youness • Asmaa Gomaa • Imam Waked• Hend M. El Tayebi •Ahmed I. Abdelaziz : miR-155: A Double Faced microRNA With Respect to its impact on Tumorigenesis in Both Natural Killer Cells and Their Target Hepatocytes, Journal of Hepatology– EASL International Liver Congress 2016, Barcelona , Spain. April 2016 , 2016.

Journal 2016

miR-29a Promotes Lipid Droplet and Triglyceride Formation in HCV Infection by Inducing Expression of SREBP-1c and CAV1

Mahdy MM, El-Ekiaby NM, Hashish RM, Salah RA, Hanafi RS, El-Said Azzazy HM, Abdelaziz AI. : miR-29a Promotes Lipid Droplet and Triglyceride Formation in HCV Infection by Inducing Expression of SREBP-1c and CAV1, Journal of Clinical and Transnational Hepatology , 2016.
doi: 10.14218/JCTH.2016.00046 2016 Dec 28;4(4):293-299

Journal 2016

miR-486-5p enhances HCC tumor suppression through repressing IGF-1R and its downstream mediators mTOR, STAT3 and c-Myc.

R.A.Youness, H.M.El-Tayebi, R.A.Assal, K.A.Hosny, G.Esmat, A.I.Abdelaziz : miR-486-5p enhances HCC tumor suppression through repressing IGF-1R and its downstream mediators mTOR, STAT3 and c-Myc., Oncology letters , 2016.

Journal 2016

New spectrofluorimetric methods for determination of melatonin in the presence of N-{2-[1-({3-[2-(acetylamino) ethyl]-5-methoxy-1H-indol-2-yl}methyl)-5-methoxy-1H-indol-3-yl]-ethyl}acetamide:a contaminant in commercial melatonin preparations

Darwish, H.W.; Attia, M.I.; Zlotos, D.P : New spectrofluorimetric methods for determination of melatonin in the presence of N-{2-[1-({3-[2-(acetylamino) ethyl]-5-methoxy-1H-indol-2-yl}methyl)-5-methoxy-1H-indol-3-yl]-ethyl}acetamide:a contaminant in commercial melatonin preparations, Chemistry Central Journal, (2016) 10:57, DOI 10.1186/s13065-016-0203-y , 2016.
Erratum to: Darwish, H.W.; Attia, M.I. Chemistry Central Journal 2012, 6:36 DOI 10.1186/1752-153X-6-36

Book Chapter 2016

Nitric Oxide Regulating Proteins as Biochemical and Genetic Markers of Coronary Artery Disease

Gad-NO chapter.pdf Mohamed Z. Gad · Sahar M. Abdel-Maksoud · Sally I. Hassanein · Ingy M. Hashad · Mohamed F. Abdel Rahman · Mohamed A. Abu el Maaty · Gamal M. Shaban · Khaled Abou-Aisha : Nitric Oxide Regulating Proteins as Biochemical and Genetic Markers of Coronary Artery Disease, In book: Biomarkers in Cardiovascular Disease, Edition: 2016, Publisher: Springer Netherlands, Editors: Vinood B. Patel, Victor R. Preedy , 2016.
DOI: 10.1007/978-94-007-7741-5_34-1

Book Chapter 2016

Nitric Oxide Regulating Proteins as Biochemical and Genetic Markers of Coronary Artery Disease

Mohamed Z. Gad, Sahar M. Abdel-Maksoud, Sally I. Hassanein, Ingy M. Hashad, Mohamed F. Abdel Rahman, Mohamed A. Abu el Maaty, Gamal M. Shaban, Khaled Abou-Aisha : Nitric Oxide Regulating Proteins as Biochemical and Genetic Markers of Coronary Artery Disease, Biomarkers in Cardiovascular Disease , 2016.

Journal 2016

Oxime Ethers of (E)-11-Isonitrosostrychnine as Highly Potent Glycine Receptor Antagonists

Mohsen, AYM; Mandour, YM; Sarukhanyan, E, Breitinger, U; Villmann, C; Banoub, M; Breitinger, HG; Dandekar, T; Holzgrabe, U; Sotriffer, C; Jensen, AA; Zlotos, DP* : Oxime Ethers of (E)-11-Isonitrosostrychnine as Highly Potent Glycine Receptor Antagonists, Journal of Natural Products, 2016, 79, 2997-3005 , 2016.

Journal 2016

Oxime Ethers of (E)-22-Isonitrosostrychnine as Highly Potent Glycine Receptor Antagonists

Mohsen, A.M.Y., Sarukhanyan, E., Breitinger, U, Villmann, C., Banoub, M., Breitinger, H.-G., Dandekar, T., Sotriffer, C., Holzgrabe, U., Jensen, A.A., Zlotos, D. P. : Oxime Ethers of (E)-22-Isonitrosostrychnine as Highly Potent Glycine Receptor Antagonists, Journal of Natural Products , 2016.

Journal 2016

Patch-Clamp Study of Hepatitis C p7 Channels Reveals Genotype-Specific Sensitivity to Inhibitors

2016 Breitinger p7 patch-clamp BPJ.pdf Ulrike Breitinger, Noha S. Farag, Nourhan K. M. Ali, and Hans-Georg A. Breitinger : Patch-Clamp Study of Hepatitis C p7 Channels Reveals Genotype-Specific Sensitivity to Inhibitors, Biophysical Journal , 2016.
IF 3.63

Conference 2016

Personalized or Impersonalized: That is the Question

Ashraf H. Abadi. : Personalized or Impersonalized: That is the Question, . Faculty of Pharmacy, Cairo University, 7th International Scientific Conference , 2016.
Keynote speaker

Book Chapter 2016

Polymorphisms in the Vitamin D Pathway in Relation to 25-Hydroxyvitamin D Status and Cardiovascular Disease Incidence: Application to Biomarkers

Gad-Vit D chapter.pdf Mohamed A. Abu el Maaty · Sally I. Hassanein · Mohamed Z. Gad : Polymorphisms in the Vitamin D Pathway in Relation to 25-Hydroxyvitamin D Status and Cardiovascular Disease Incidence: Application to Biomarkers, In book: Biomarkers in Cardiovascular Disease, Edition: 2016, Publisher: Springer Netherlands, Editors: Vinood B. Patel, Victor R. Preedy , 2016.
DOI: 10.1007/978-94-007-7741-5_23-1

Conference 2016

Restoring The Expression of Endogenous IGF-1 by miR-486 in NK Cells of HCC Patients Augments Its Cytotolytic Activity Against Hepatoma Cell Lines

Rana A. Youness*, Mai A. Rahmoon, Asmaa Gomaa, Imam Waked, Gamal Esmat, Hend M. El Tayebi, Ahmed I. Abdelaziz. : Restoring The Expression of Endogenous IGF-1 by miR-486 in NK Cells of HCC Patients Augments Its Cytotolytic Activity Against Hepatoma Cell Lines, Journal of Hepatology– EASL International Liver Congress, Barcelona, Spain, April 2016 , 2016.

Journal 2016

Synthesis and Optimization of New 3,6-disubstitutedindole Derivatives and Their Evaluation as Anticancer Agents Targeting the MDM2/MDMx Complex.

76. Mohamed SalahRezk, Mohammad Abdel-Halim, Adam Keeton, DerekFranklin, Matthias Bauer, Frank Michael Boeckler,Matthias Engel, Rolf Wolfgang Hartmann,Yanping Zhang, Gary Anthony Piazza, Ashraf HassanAbadi. : Synthesis and Optimization of New 3,6-disubstitutedindole Derivatives and Their Evaluation as Anticancer Agents Targeting the MDM2/MDMx Complex. , Chemical and Pharmaceutical bulletin (Tokyo) , 2016.
64(1), 34-41 (2016).

Conference 2016

Tamarix articulata, quercetin and epigallocatechin gallate destabilize the interplay between miR-615-5p, miR-1275 and IGF2BPs, in molecular targets of hepatocellular carcinoma

Yasmin M. Shaalan, Rana A. Youness, Mai A. Rahmoon, Reem A. Assal, Heba Handoussa, Hend M. El Tayebi, Ahmed I. Abdelaziz : Tamarix articulata, quercetin and epigallocatechin gallate destabilize the interplay between miR-615-5p, miR-1275 and IGF2BPs, in molecular targets of hepatocellular carcinoma, Planta Medica-9th Joint Natural Product Conference 2016, Copehagen, Denmark, , 2016.

Conference 2016

The in vivo triad behind the neuromodulatory effect of Bauhinia variegata L

Alaa Selim, Heba Handoussa, Nesrine El Sayed. : The in vivo triad behind the neuromodulatory effect of Bauhinia variegata L, 5th International Conference on Alzheimer’s Disease & Dementia , 2016.

Journal 2016

Update on melatonin receptors: IUPHAR Review 20.

Jockers R, Delagrange P, Dubocovich ML, Markus RP, Renault N, Tosini G, Cecon E, Zlotos DP. : Update on melatonin receptors: IUPHAR Review 20., British Journal of Pharmacology, 2016, 173(18), 2702-25. , 2016.

2015

Conference 2015

Is there a correlation between connexin 37 C1019T polymorphism and Incidence of acute Myocardial infarction in the Egyptians?

: Is there a correlation between connexin 37 C1019T polymorphism and Incidence of acute Myocardial infarction in the Egyptians? , The 29th Annual Symposium of The Protein Society - Barcelona – Spain , 2015.

Conference 2015

Controlling hepatocyte lipid droplet proteins through regulation of SREBP-1c and caveolin-2 by miR-29a in HCV infected cell models

Mennatallah M. Mahdy · Nada El-Ekiaby · Noha M. Elemam · Shereen A. ElSobky · Rasha Hanafi · Ahmed I. Abdelaziz : Controlling hepatocyte lipid droplet proteins through regulation of SREBP-1c and caveolin-2 by miR-29a in HCV infected cell models, Monothematic Conference: 'Microbiota, Metabolism and NAFLD, Innsbruck, Austria. , 2015.

Conference 2015

A novel celecoxib derivative that lacks COX-2 inhibition but displays potent colon tumor cell growth and PDE5 inhibitory activity

Sara C. Sigler, Veronica Ramirez-Alcantara, Adam B. Keeton, Mohammad Abdel-Halim, Ashraf H. Abadi, Gary A. Piazza : A novel celecoxib derivative that lacks COX-2 inhibition but displays potent colon tumor cell growth and PDE5 inhibitory activity, American association for Cancer Research AACR annual meeting. , 2015.
Pennsylvania, USA. April 2015.

Journal 2015

Addressing the link between paraoxonase-1 gene variants and the incidence of early onset myocardial infarction

Mohamed F. Abdel Rahman, Ingy M. Hashad, Khaled Abou-Aisha, Sahar M. Abdel-Maksoud, and Mohamed Z. Gad : Addressing the link between paraoxonase-1 gene variants and the incidence of early onset myocardial infarction, Arch Med Sci. , 2015.

Journal 2015

Addressing the Link between Paraoxonase-1 Gene Variants and the Incidence of Early Onset Myocardial Infarction

Mohamed F. Abdel Rahman, Ingy M. Hashad, Khaled Abou-Aisha, Sahar M. Abdel-Maksoud, Mohamed Z. Gad : Addressing the Link between Paraoxonase-1 Gene Variants and the Incidence of Early Onset Myocardial Infarction, Archives of Medical Science , 2015.
11(3): 513-520

Patent 2015

Allosteric Inhibitors of Atypical Protein Kinases C

Abadi patent 2015 WO2015075051A1.pdf Matthias Engel, Mohammad Abdel-Halim, Ashraf H. Abadi, : Allosteric Inhibitors of Atypical Protein Kinases C, Allosteric Inhibitors of Atypical Protein Kinases C , 2015.
WO2015075051; PCT/EP2014/074971

Patent 2015

Allosteric Inhibitors of Atypical Protein Kinases C

Matthias Engel, Mohammad Abdel-Halim and Ashraf H. Abadi : Allosteric Inhibitors of Atypical Protein Kinases C, - , 2015.
PCT WO/2015/075051

Conference 2015

An Alternative Prodrug Approach to Improve Pharmacogenomic Susceptibility of Tamoxifen and its Flexible Analogues

Nehal H. ELGhazawy , Ashraf. H. Abadi , Rolf Hartmann , Matthias Engel, Nermin S. Ahmed : An Alternative Prodrug Approach to Improve Pharmacogenomic Susceptibility of Tamoxifen and its Flexible Analogues, Duphat , 2015.

Conference 2015

At the Cross line between Celecoxib and Sildenafil.

Ashraf H. Abadi. : At the Cross line between Celecoxib and Sildenafil. , 3rd FUE-International Conference on Pharmaceutical Sciences. , 2015.
Cairo, Egypt. February 2015.

Conference 2015

C2-Linked Dimeric Strychnine Analogues as Bivalent Ligands Targeting Glycine Receptors

Zlotos, D. P.; Banoub, M.; Breitinger, U.; Holzgrabe, U.; Villmann, C.; Breitinger, H-G. : C2-Linked Dimeric Strychnine Analogues as Bivalent Ligands Targeting Glycine Receptors , Annual Meeting of the German Pharmaceutical Society, Duesseldorf, Germany, poster presentation , 2015.

Conference 2015

Cell Specific and Contradicting Functions of miR-615-5p and miR-155 in both Natural Killer cells and their Target Hepatocytas In Hepatocellular Carcinoma.

M.A. Rahmoon, R.A. Youness, A. Gomaa, I. Waked, H.M. El Tayebi, A.l. Abdelaziz : Cell Specific and Contradicting Functions of miR-615-5p and miR-155 in both Natural Killer cells and their Target Hepatocytas In Hepatocellular Carcinoma., The liver meeting, American Association for the study of liver disease, At San Francisco, California, United states , 2015.

Conference 2015

Cell Specific and Contradicting Functions of miR-615-5p and miR-155 in both Natural Killer cells and their Target Hepatocytes in Hepatocellular Carcinoma.

Mai A. Rahmoon, Rana A. Youness, Asmaa Gomaa, Imam Waked, Gamal Esmat, Hend M. El Tayebi, Ahmed I. Abdelaziz. : Cell Specific and Contradicting Functions of miR-615-5p and miR-155 in both Natural Killer cells and their Target Hepatocytes in Hepatocellular Carcinoma., American Associatiation for the Study of Liver disease (AASLD)-The liver meeting 2015 , 2015.
Hepatology- American Associatiation for the Study of Liver disease (AASLD)-The liver meeting 2015, San Francisco-California,USA. November 2015 (poster presentation)

Journal 2015

Chitosan Nanoparticles for Nuclear Targeting: The Effect of Nanoparticle Size and Nuclear Localization Sequence Density

Tammam SN, Azzazy HM, Breitinger HG, Lamprecht A. (2015) : Chitosan Nanoparticles for Nuclear Targeting: The Effect of Nanoparticle Size and Nuclear Localization Sequence Density, Molecular Pharmacology , 2015.
Mol Pharm. 12, 4277-4289 IF 2015 4.8

Conference 2015

Contribution of Connexin37 Gene Polymorphism (C1019T) in the Incidence of Acute Myocardial Infarction in the Egyptians

Fadwa El Tahry, Ingy Hashad, Mohamed Farouk, Mohamed Z. Gad : Contribution of Connexin37 Gene Polymorphism (C1019T) in the Incidence of Acute Myocardial Infarction in the Egyptians , 29th Annual Symposium of the Protein Society, Barcelona, Spain , 2015.
July 22-25

Conference 2015

Contribution of MTHFR and Paraoxonase Gene Polymorphism in the Predisposition of Acute Myocardial Infarction in Egyptians

Ingy M. Hashad , Mohamed F. Abdel Rahman, Mohamed Z. Gad, Michael Bader, Gamal Shaaban : Contribution of MTHFR and Paraoxonase Gene Polymorphism in the Predisposition of Acute Myocardial Infarction in Egyptians, 12th National Conference of Biochemistry & Molecular Biology and their role in development and environment, Cairo, Egypt , 2015.
Mar. 15 –17

Conference 2015

Contribution of RANTES (-460) G/A, CD14 (-260) C/T and IL-6 174 G/C Gene Polymorphism in the Incidence of Acute Myocardial Infarction.

Ingy M. Hashad , Mohamed F. Abdel Rahman, Mohamed Z. Gad, Michael Bader, Natalia Alenina : Contribution of RANTES (-460) G/A, CD14 (-260) C/T and IL-6 174 G/C Gene Polymorphism in the Incidence of Acute Myocardial Infarction. , 12th National Conference of Biochemistry & Molecular Biology and their role in development and environment, Cairo, Egypt , 2015.
Mar. 15 –17

Conference 2015

Controlling Hepatocyte Lipid Droplet Proteins Through Regulation of SREBP-1c And Caveolin-2 By miR-29a in HCV Infected Cell Models

Mennatallah M. Mahdy, Nada El-Ekiaby, Noha M. Elemam, Shereen A. ElSobky, Rasha Hanafi, Ahmed I. Abdelaziz : Controlling Hepatocyte Lipid Droplet Proteins Through Regulation of SREBP-1c And Caveolin-2 By miR-29a in HCV Infected Cell Models, Journal of Hepatology– EASL Monothematic Conference: Microbiota, Metabolism and NAFLD 2015 Austria , 2015.

Journal 2015

Crystal structure of 5,11-dihydropyrido-[2,3-b][1,4]benzodiazepin-6-one

Noura M. Riad, Darius P. Zlotos*, and Ulrike Holzgrabe : Crystal structure of 5,11-dihydropyrido-[2,3-b][1,4]benzodiazepin-6-one, Acta_Crystallographica E, , 2015.
Acta Cryst. (2015). E71, o304–o305

Journal 2015

D1-like receptors distinguishing thieno-azecine regioisomers.

Abdel-Fattah, Mohamed A. O.; Abadi, Ashraf H.; Lehmann, Jochen; Schweikert, Peter M.; Enzensperger, Christoph. : D1-like receptors distinguishing thieno-azecine regioisomers., MedChemComm , 2015.
6, 1679-1686 (2015).

Conference 2015

Dasatinib modulates M1/M2 polarization and improves cognitive deficits in a mouse model of neuroinflammation

El-Sallab H.T, Abdel-Kader R.M and Hamdi N : Dasatinib modulates M1/M2 polarization and improves cognitive deficits in a mouse model of neuroinflammation, The 12th International Conference on Alzheimer's and Parkinson's Diseases and related neurological disorders , 2015.

Conference 2015

Dasatinib suppresses neuroinflammation-induced cognitive deficits and neurodegeneration through Src tyrosine kinases mechanism

El-Sallab H.T, Abdel-Kader R.M, Zekry M. and Hamdi N : Dasatinib suppresses neuroinflammation-induced cognitive deficits and neurodegeneration through Src tyrosine kinases mechanism, The 3rd International Conference on Alzheimer’s Disease & Dementia, Toronto, Canada , 2015.

Journal 2015

Design and Synthesis of Novel Phenylpiperazine Derivatives as

Arch Parm PUBLISHED PAPER.pdf : Design and Synthesis of Novel Phenylpiperazine Derivatives as, Archiv der Pharmazie , 2015.

Journal 2015

Design and Synthesis of Novel Phenylpiperazine Derivatives as Potential Anticonvulsant Agents

Habib MM, Abdelfattah MA, Abadi AH. : Design and Synthesis of Novel Phenylpiperazine Derivatives as Potential Anticonvulsant Agents, Arch Pharm (Weinheim). , 2015.
348, 868-74 (2015)

Conference 2015

Design-of-Experiment Approach for Determination of Fat soluble Vitamins on Core-Shell Technology Stationary Phase by HPLC.

Norhan Elgizawy, Rasha Hanafi : Design-of-Experiment Approach for Determination of Fat soluble Vitamins on Core-Shell Technology Stationary Phase by HPLC. , HPLC2015 , 2015.
42nd international symposium on high performance liquid phase separations and related techniques, Geneva, Switzerland.

Journal 2015

Design-of-Experiment approach for HPLC analysis of 25-HydroxyvitaminD. A comparative assay with ELISA

Mohamed Abdulla Abu el Maaty, Rasha Sayed Hanafi, Hassan Y. Aboul-Enein, Mohamed Zakaria Gad : Design-of-Experiment approach for HPLC analysis of 25-HydroxyvitaminD. A comparative assay with ELISA, J Chromatogr Sci. , 2015.
53 (1): 66-72

Conference 2015

Despite Repressing IGF-1R, miR-181a Halts The Tumor-Suppressor Activity of Decorin by Ehnancing Tumor Progression in Hepatocellular Carcinoma

Reem A. Assal, Hend M. El Tayebi, Karim A. Hosny, Gamal Esmat, Ahmed I. Abdelaziz : Despite Repressing IGF-1R, miR-181a Halts The Tumor-Suppressor Activity of Decorin by Ehnancing Tumor Progression in Hepatocellular Carcinoma, Journal of Hepatology– EASL International Liver Congress 2015 (Vienna, Austria) , 2015.

Journal 2015

Discovery of Nanomolar Dengue and West Nile Virus Protease Inhibitors Containing a 4-Benzyloxyphenylglycine Residue

Behnam, M. A. M,; Graf, D.; Bartenschlager, R.; Zlotos, D. P.; Klein. C. : Discovery of Nanomolar Dengue and West Nile Virus Protease Inhibitors Containing a 4-Benzyloxyphenylglycine Residue, Journal of Medicinal Chemistry, DOI:10.1021/acs.jmedchem.5b01441 , 2015.

Conference 2015

Enhancing Natural Killer cells Cytotoxicity by miR-486-5p in Hepatocellular Carcinoma

Rana A. Youness, Mai A. Rahmoon, Asmaa I. Gomaa, Imam Waked, Gamal Esmat, Hend M. El Tayebi, Ahmed I. Abdelaziz : Enhancing Natural Killer cells Cytotoxicity by miR-486-5p in Hepatocellular Carcinoma, Journal of Molecular and Genetic Medicine , 2015.
Oral Presentation- 5th International Conference on Genomics and Pharmacogenomics, Texas, USA

Conference 2015

Enhancing natural killer cytotoxicity by miR-486-5p in hepatocellular carcinoma

Rana A. Youness, Mai A. Rahmoon, Asmaa Gomaa, Imam Waked, Gamal Esmat, Hend M. El Tayebi, Ahmed I. Abdelaziz : Enhancing natural killer cytotoxicity by miR-486-5p in hepatocellular carcinoma, 3rd International conference on Genomics and pharmacogenomics , 2015.
Journal of Molecular Medicine - 3rd International conference on Genomics and pharmacogenomics, San Antonio-Texas, USA. September 2015 (Oral Presentation)

Conference 2015

Epigenetic Harnessing of HCV Via Modulating The Lipid DROPLET-Proteins, ADRP AND TIP47, in HCV Cell Models

Nada El-Ekiaby, Radwa Y. Mekky, Mohammad El-Sayed, Gamal Esmat, Ahmed I. Abdelaziz : Epigenetic Harnessing of HCV Via Modulating The Lipid DROPLET-Proteins, ADRP AND TIP47, in HCV Cell Models, Journal of Hepatology– EASL International Liver Congress 2015 (Vienna, Austria) , 2015.

Journal 2015

Genetic variation in vitamin D receptor gene (Fok1:rs2228570) is associated with risk of coronary artery disease

Mohamed A. Abu El Maaty, Sally I. Hassanein, Mohamed Z. Gad : Genetic variation in vitamin D receptor gene (Fok1:rs2228570) is associated with risk of coronary artery disease, Biomarkers , 2015.
12/2015; DOI:10.3109/1354750X.2015.1118535

Journal 2015

Glucose and related sugars are allosteric potentiators of glycine receptor ion channels

2015 GlyR modulation by glucose.pdf Breitinger, U., Raafat, K., Breitinger, H.-G. (2015) : Glucose and related sugars are allosteric potentiators of glycine receptor ion channels, Journal of Neurochemistry , 2015.
J. Neurochem. 134, 1055-1066. IF 2015 4.28 Selected as "Key Scientific Article" by Global Medical Discovery

Conference 2015

Glycyrrhizin attenuates oxidative stress and neuro-inflammation: novel approach targeting Alzheimer's disease

Nadia M. Sharaf, Ragwa M. Abdelghany, Nesrine S. El Dine, Laila G. Mahran : Glycyrrhizin attenuates oxidative stress and neuro-inflammation: novel approach targeting Alzheimer's disease, 12th, International conference on Alzheimer's & Parkinson's disease, (AD/PD 2015), Nice, France , 2015.

Conference 2015

HPLC Determination of the Levels of 6-MP Metabolites and its Relation to Risk of Drug Toxicity among Egyptian Children with Acute Lymphocytic Leukemia.

Eman Abdelsayed, Sahar Abdelmaksoud, Iman Sidhom, Mohamed Gad, Rasha Hanafi : HPLC Determination of the Levels of 6-MP Metabolites and its Relation to Risk of Drug Toxicity among Egyptian Children with Acute Lymphocytic Leukemia., HPLC2015 , 2015.
42nd international symposium on high performance liquid phase separations and related techniques, Geneva, Switzerland.

Conference 2015

Improving Natural Killer Cells Cytotoxicty and Harnessing Hepatocyte Cancer Progression by miR-486-5P

Aya A. Bassiouni, Mai A. Rahmoon, Rana A. Youness, Asmaa I. Gomaa, Imam Waked, Gamal Esmat, Hend M. El Tayebi, Ahmed I. Abdelaziz : Improving Natural Killer Cells Cytotoxicty and Harnessing Hepatocyte Cancer Progression by miR-486-5P, Journal of Hepatology, EASL International Liver Congress 2015 (Vienna, Austria) , 2015.

Conference 2015

Improving Natural Killer Cells Cytotoxicty and Harnessing Hepatocyte Cancer Progression by miR-486-5P

Aya A. Bassiouni, Mai A. Rahmoon, Rana A. Youness, Asmaa I. Gomaa, Imam Waked, Gamal Esmat, Hend M. El Tayebi, Ahmed I. Abdelaziz : Improving Natural Killer Cells Cytotoxicty and Harnessing Hepatocyte Cancer Progression by miR-486-5P, Journal of Hepatology, EASL International Liver Congress 2015 (Vienna, Austria), 2015 , 2015.
Ranked From Top 10% posters in the conference. Nominated for an oral Presentation.

Conference 2015

Improving Natural Killer Cells Cytotoxicty and Harnessing Hepatocyte Cancer Progression by miR-486-5p

Aya A. Bassiouni, Mai A. Rahmoon, Rana A. Youness, Asmaa I. Gomaa, Imam Waked, Gamal Esmat, Hend M. El Tayebi, Ahmed I. Abdelaziz : Improving Natural Killer Cells Cytotoxicty and Harnessing Hepatocyte Cancer Progression by miR-486-5p , Journal of Hepatology, EASL International Liver Congress 2015 (Vienna, Austria), 2015. , 2015.
Ranked From Top 10% posters in the conference. Nominated for an oral Presentation.

Conference 2015

INFLUENCE OF GC GENE POLYMORPHISM (rs2282679) ON CIRCULATING 25- HYDROXYVTAMIN D LEVELS AND CORONARY ARTERY DISEASE INCIDENCE

S.I.Hassanein, N.K.Sedky, M.A. Abu el Maaty, M.Z. Gad : INFLUENCE OF GC GENE POLYMORPHISM (rs2282679) ON CIRCULATING 25- HYDROXYVTAMIN D LEVELS AND CORONARY ARTERY DISEASE INCIDENCE, 18th Workshop on Vitamin D, Delft, the Netherlands , 2015.
Apr. 21-24

Conference 2015

Internationalization of Science and Research in Egypt

Ashraf H. Abadi : Internationalization of Science and Research in Egypt, Europe and Mediterranean Regions: History, Emergencies, and Chances , 2015.
Lecce, Italy. April 2015

Conference 2015

Investigation of brain-derived neurotrophic factor (BDNF) gene expression in hypothalamus of obese rats: Modulation by omega-3 fatty acids.

Sahar M. Abdel-Maksoud, Sally I. Hassanein, Neveen A. Gohar, Saad. M. Attia, Mohamed Z. Gad : Investigation of brain-derived neurotrophic factor (BDNF) gene expression in hypothalamus of obese rats: Modulation by omega-3 fatty acids. , 6th International Conference on Fixed Combination in the Treatment of Hypertension, Dyslipidemia and Diabetes Mellitus, Berlin, Germany , 2015.
Mar. 26-29

Conference 2015

Investigation of genetic recombination of hepatitis C virus in patients infected with genotypes 1, 2 and 4

J. Dietz, N. Hamdi, S. Susser, K.-H. Peiffer, C Berkowski, D. Perner, S. Zeuzem, C. Sarrazin : Investigation of genetic recombination of hepatitis C virus in patients infected with genotypes 1, 2 and 4, EASL, the 50th International Liver Congress , 2015.

Conference 2015

Is there a correlation between 174 (G/C) polymorphism of Il-6 Gene and the incidence of acute myocardial infarction?

Ingy Hshad, Habiba Nosseir, Mohamed Abdel Rahman, Mohamed Gad and Gamal Shaaban : Is there a correlation between 174 (G/C) polymorphism of Il-6 Gene and the incidence of acute myocardial infarction?, 21st IFCC-EFLM European Congress of Clinical Chemistry and Laboratory Medicine, Paris, France , 2015.
June 21-25

Conference 2015

Is there a correlation between 174(G/C) Polymorphism of IL-6 gene and the incidence of Acute Myocardial infarction?

: Is there a correlation between 174(G/C) Polymorphism of IL-6 gene and the incidence of Acute Myocardial infarction?, The 21st IFCC-EFLM European Congress of Clinical Chemistry and Laboratory Medicine - Euromedlab, Paris , 2015.

Journal 2015

Methylene Blue Improves Brain Mitochondrial ABAD Functions and Decreases Aß in a Neuroinflammatory Alzheimer's Disease Mouse Model

Zakaria A, Hamdi N, Abdel-Kader RM : Methylene Blue Improves Brain Mitochondrial ABAD Functions and Decreases Aß in a Neuroinflammatory Alzheimer's Disease Mouse Model, Mol. Neurobiol. , 2015.

Journal 2015

Mining ZINC Database to Discover Potential Phosphodiesterase 9 Inhibitors Using Structure-Based Drug Design Approach

Hassaan EA, Sigler SC, Ibrahim TM, Lee KJ, Cichon LK, Gary BD, Canzoneri JC, Piazza GA, Abadi AH. : Mining ZINC Database to Discover Potential Phosphodiesterase 9 Inhibitors Using Structure-Based Drug Design Approach, Med Chem , 2015.
Dec 3. [Epub ahead of print]

Journal 2015

Minocycline attenuates Aß oligomers-induced pro-inflammatory phenotype in primary microglia while enhancing Aß fibrils phagocytosis

El-Shimy I.A, Heikal O. and Hamdi N : Minocycline attenuates Aß oligomers-induced pro-inflammatory phenotype in primary microglia while enhancing Aß fibrils phagocytosis, Neuroscience Letters, Volume 609, 16 November 2015, Pages 36–41 , 2015.
Free access until December 6, 2015 under http://authors.elsevier.com/a/1RuCb15DX19s3r Audioslides are available under http://audioslides.elsevier.com/getvideo.aspx?doi=10.1016/j.neulet.2015.10.024

Book 2015

miR-486-5p and Liver Cancer Therapy: A Beautiful Mind Act

My Book_Coverpreview.pdf Rana Ahmed Youness Mai Atef Rahmoon Ahmed Ihab Abdelaziz : miR-486-5p and Liver Cancer Therapy: A Beautiful Mind Act, Lambert Academic Publishing , 2015.

Conference 2015

Modulating the Expression of the Activating Receptor NKG2D and the Inhibitory Receptor NKG2A of NK cells by miR-182 in HCC

Mohamed M. Abdelrahman, Injy O. Fawzy, Asmaa I. Gomaa, Imam Waked, Gamal Esmat, Hend M. El Tayebi, Ahmed I. Abdelaziz : Modulating the Expression of the Activating Receptor NKG2D and the Inhibitory Receptor NKG2A of NK cells by miR-182 in HCC, Clinical Epigenetics-CLEPSO Meeting 2015 (Düsseldorf, Germany) , 2015.

Conference 2015

Neuro-protective effect of Thymoquinone against lipopolysaccharide-induced behavioral and neurotransmitter alteration in an animal model

Nadia M. Sharaf, Ragwa M. Abdelghany, Nesrine S. El Dine, Laila G. Mahran : Neuro-protective effect of Thymoquinone against lipopolysaccharide-induced behavioral and neurotransmitter alteration in an animal model, 12th, International conference on Alzheimer's & Parkinson's disease, (AD/PD 2015), Nice, France , 2015.

Conference 2015

NMDAR2B is overexpressed in neurodegeneration: modulation by NOS inhibitors

Ahmed Maher, Nesrine Salah ElDin, Hans G. Breitinger, Mohamed Z. Gad : NMDAR2B is overexpressed in neurodegeneration: modulation by NOS inhibitors, THE LANCET Neurology AUTOIMMUNE DISORDERS CONFERENCE, Barcelona, Spain , 2015.
Mar. 26-27

Journal 2015

Novel Difluoroacetamide Analogues of Agomelatine and Melatonin: Probing the Melatonin Receptors for MT1-Selectivity

Zlotos, D.P.; Riad, N.; Osman, M.B.; Dodda, B.R.; Witt-Enderby, P.A. : Novel Difluoroacetamide Analogues of Agomelatine and Melatonin: Probing the Melatonin Receptors for MT1-Selectivity, Medicinal Chemistry Communications , 2015.
2015, 6(7), 1340-1344.

Conference 2015

Role of microRNAs as Novel Biomarkers in Cardiovascular Disease: Highlights on miRNAs 133a and 208b

Sally I. Hassanein, Ahmed Hegazy, Dina Kamal, Khaled Abou-Aisha, Mohamed Z. Gad : Role of microRNAs as Novel Biomarkers in Cardiovascular Disease: Highlights on miRNAs 133a and 208b, 12th National Conference of Biochemistry & Molecular Biology and their role in development and environment, Cairo, Egypt , 2015.
Mar. 15 –17

Conference 2015

Serum Endothelin and NO Concentrations Contribute More than the Genotype to the Risk of Early-Onset Acute Myocardial Infarction in Egyptians

Mohamed F. Abdel Rahman, Ingy M. Hashad, Khaled Abou-Aisha, Sahar M. Abdel Maksoud, Mohamed Z. Gad : Serum Endothelin and NO Concentrations Contribute More than the Genotype to the Risk of Early-Onset Acute Myocardial Infarction in Egyptians, 12th National Conference of Biochemistry & Molecular Biology and their role in development and environment, Cairo, Egypt , 2015.
Mar. 15 –17

Journal 2015

Structural docking studies of COX-II inhibitory activity for metabolites derived from Corchorus olitorius and Vitis vinifera

Yasmine Mandour · Heba Handoussa · Noha Swilam · Rasha Hanafi · Laila Mahran : Structural docking studies of COX-II inhibitory activity for metabolites derived from Corchorus olitorius and Vitis vinifera, International Journal of Food Properties , 2015.
DOI:10.1080/10942912.2015.1114492

Journal 2015

Structural docking studies of COX-II inhibitory activity for quercetin metabolites derived from Corchorus Olitorius and Vitis Vinifera

Heba Handoussa,Yasmine Mandour, Noha Swilam, Rasha Hanafi and Laila Mahran : Structural docking studies of COX-II inhibitory activity for quercetin metabolites derived from Corchorus Olitorius and Vitis Vinifera, International Journal of Food Properties , 2015.

Journal 2015

Structure-based design of novel tetrahydro-beta-carboline derivatives with a hydrophilic side chain as potential phosphodiesterase inhibitors

Ahmed K. Elhady, Sara C. Sigler, Nazih Noureldin, Joshua C. Canzoneri, Nermin S. Ahmed,Gary A. Piazza, Ashraf H. Abadi : Structure-based design of novel tetrahydro-beta-carboline derivatives with a hydrophilic side chain as potential phosphodiesterase inhibitors, Sci. Pharm. , 2015.

Journal 2015

Synthesis and application of a molecularly imprinted polymer for the voltammetric determination of famciclovir

Nesrine Abdelrehim El Gohary Adel Madbouly Rasha Mohamed El Nashar Boris Mizaikoff : Synthesis and application of a molecularly imprinted polymer for the voltammetric determination of famciclovir, Biosensors and Bioelectronics , 2015.

Conference 2015

Triangular relationship between single nucleotide polymorphism in the CYP2R1 gene (FOKI and MNII), 25-hydroxyvitamin D level, and coronary artery disease incidence

Mohamed A. Abu el Maaty, Sally I, Hassanein, Hameis M. Sleem and Mohamed Z. Gad : Triangular relationship between single nucleotide polymorphism in the CYP2R1 gene (FOKI and MNII), 25-hydroxyvitamin D level, and coronary artery disease incidence, 18th Workshop on Vitamin D, Delft, the Netherlands , 2015.
Apr. 21-24

Conference 2015

Understanding the Link between Vitamin D Deficiency and Cardiovascular Disease

Mohamed Z. Gad : Understanding the Link between Vitamin D Deficiency and Cardiovascular Disease, 12th National Conference of Biochemistry & Molecular Biology and their role in development and environment, Cairo, Egypt , 2015.
Mar. 15 –17

2014

Journal 2014

1,3,5-trisubstituted pyrazolines as potent and highly selective inhibitors of protein kinasce C-zeta.

Mohammad Abdel-Halim, Britta diesel , Alexandra K. Kiemer, Ashraf H. Abadi, Rolf W. Hartmann, Matthias Engel : 1,3,5-trisubstituted pyrazolines as potent and highly selective inhibitors of protein kinasce C-zeta., J. Med. Chem , 2014.
57, 6513-30 (2014).

Conference 2014

A COACH, A PLAYMAKER, A DEFENDER AND STRIKERS: AN EPIGENETIC-TARGET INTERPLAY IN HCV/HCC

M.M. Fouad, N.M. Elemam, H.B. Sherif, S.A. El Sobky, R.A. Yacoub, A.K. Abelhamid, T. Elbaz, M.A. Mohey El Din, I.O. Fawzy, H.M. El Tayebi, N. El-Ekiaby, R.Y. Mekky, G. Esmat, A.I. Abdelaziz : A COACH, A PLAYMAKER, A DEFENDER AND STRIKERS: AN EPIGENETIC-TARGET INTERPLAY IN HCV/HCC, Journal of Hepatology EASL – International Liver Congress 2014 (London,United Kingdom) , 2014.

Conference 2014

A novel series of celecoxib derivatives lacking COX-2 inhibitory activity more potently inhibits cancer cell growth by inhibiting PDE5.

Sara C. Sigler, Veronica Ramirez, Ashraf Abadi, Gary Piazza : A novel series of celecoxib derivatives lacking COX-2 inhibitory activity more potently inhibits cancer cell growth by inhibiting PDE5., American Association for Cancer Research (AACR), annual meeting , 2014.
San Diego, USA. 5-9 April 2014

Conference 2014

A Novel Series of Celecoxib Derivatives that Inhibit PDE 5 but Lack COX-2 Inhibitory Activity Potently Inhibit Colon Cancer Cell Growth.

Sara C. Sigler, Ashraf H. Abadi, and Gary A. Piazza : A Novel Series of Celecoxib Derivatives that Inhibit PDE 5 but Lack COX-2 Inhibitory Activity Potently Inhibit Colon Cancer Cell Growth. , Gordon research Conference, Cyclic Nucleotide Phosphodiesterases, Signaling Regulation in the Pathogenesis and Treatment of Disease , 2014.
Massachussete, USA. 1-6 June 2014

Journal 2014

A pleiotropic effect of the single clustered hepatic metastamiRs miR-96-5p & miR-182-5p on IGF-1R, IGFBP-3 and IGF-II in Hepatocellular carcinoma

Assal RA, El Tayebi HM, HosnyKA, Esmat G , Abdelaziz AI : A pleiotropic effect of the single clustered hepatic metastamiRs miR-96-5p & miR-182-5p on IGF-1R, IGFBP-3 and IGF-II in Hepatocellular carcinoma, Mol. Med. Rep , 2014.

Conference 2014

Altered expression of miR-181a in NK cells isolated from breast cancer patients

Mona Rady1, Carsten Watzl2, Maren Claus2, Ola Khorshid3, Laila Mahran1, Khaled Abou-Aisha1 : Altered expression of miR-181a in NK cells isolated from breast cancer patients, 44th annual meeting of the German society for immunology, Bonn, Germany , 2014.

Journal 2014

An Efficient and Green One-Pot Synthesis of Novel Spirooxindole Derivatives with Potential Anti-tumor Activity in an Aqueous Solvent.

abadi chem rapid comm 2014_2.pdf Lobna M. Elwarraky, Mohamed A. O. Abdel-Fattaha, Bernard D. Gary, Gary A. Piazzab, Ashraf H. Abadi : An Efficient and Green One-Pot Synthesis of Novel Spirooxindole Derivatives with Potential Anti-tumor Activity in an Aqueous Solvent. , Chem rapid Comm , 2014.
2, 33-40 (2014).

Conference 2014

Association of Vitamin D Receptor Gene Polymorphism (Fok1:rs2228570) with Risk of Coronary Artery Disease

Mohamed A. Abu el Maaty, Sally I. Hassanein and Mohamed Z Gad : Association of Vitamin D Receptor Gene Polymorphism (Fok1:rs2228570) with Risk of Coronary Artery Disease, Vitamin D and Human Health: From the Gamete to the Grave , 2014.
London, Queen Mary, University of London , 23–25 April

Conference 2014

C2- and O-Linked Melatonin Dimers as Bivalent Ligands Targeting Dimeric Melatonin Receptors

Zlotos, D. P.; Sadek, M. S.; Tadros, S. A. A.; Gerbier, R.; Jockers, R. : C2- and O-Linked Melatonin Dimers as Bivalent Ligands Targeting Dimeric Melatonin Receptors, Annual Meeting of German Pharmaceutical Society, Frankfurt, 2014 , 2014.
Poster presentation

Journal 2014

C242T polymorphism of NADPH oxidase p22phox gene reduces the risk of coronary artery disease in a random sample of Egyptian population

Ingy M. Hashad • Mohamed F. Abdel Rahman • Sahar M. Abdel-Maksoud • Khalda S. Amr • Laila K. Effat • Gamal M. Shaban • Mohamed Z. Gad : C242T polymorphism of NADPH oxidase p22phox gene reduces the risk of coronary artery disease in a random sample of Egyptian population, Mol Biol Rep , 2014.
4 January 2014

Journal 2014

C242T polymorphism of NADPH oxidase p22phox gene reduces the risk of coronary artery disease in a random sample of Egyptian population

Ingy M. Hashad, Mohamed F. Abdel Rahman, Sahar M. Abdel-Maksoud, Khalda S. Amr, Laila K. Effat, Gamal M. Shaban, Mohamed Z. Gad : C242T polymorphism of NADPH oxidase p22phox gene reduces the risk of coronary artery disease in a random sample of Egyptian population , Molecular Biology Reports , 2014.

Journal 2014

Chemical Composition and Biological Activity of Essential Oils of Cumin and Coriander Fruits from Egypt

65. Rasha S. Hanafi, Mansour S. Mohamed, Mohamed Ashour, Mona Z. El-Readi, Said Y. Desouky, Raimnd R. Niess, Ashraf H. Abadi, Michael M. Wink : Chemical Composition and Biological Activity of Essential Oils of Cumin and Coriander Fruits from Egypt, Nat. Prod. J. , 2014.
4, 63-69 (2014).

Journal 2014

Chemical composition and biological activity of essential oils of cumin and coriander fruits from Egypt.

Hanafi, R. S., Sobeh, M., Ashour, M. L., El-Readi, M. Z., Desouky, S. Y., Niess, R., Abad, A. H. and Wink, M. : Chemical composition and biological activity of essential oils of cumin and coriander fruits from Egypt., The Natural Product Journal , 2014.
4

Conference 2014

Contribution of Oxidative Stress and Gene Polymorphism in the Predisposition of Acute Myocardial Infarction

Ingy M Hashad, Mohamed F Abdel Rahman, Sahar M Abdel-Maksoud, Khalda S Amr, Gamal M Shaban, Mohamed Z Gad : Contribution of Oxidative Stress and Gene Polymorphism in the Predisposition of Acute Myocardial Infarction, 41th Annual Conference of the Egyptain Soceity of Cardiology – (Cardio Egypt 2014) , 2014.
24 Feb 2014

Conference 2014

Contribution Of The NADPH Oxidase Gene Polymorphism In The Predisposition Of Acute Myocardial Infarction In Egyptian Population

Ingy M. Hashad, Mohamed F. Abdel Rahman, Sahar M. Abdel-Maksoud, Khalda S. Amr, Gamal M. Shaban, Mohamed Z. Gad : Contribution Of The NADPH Oxidase Gene Polymorphism In The Predisposition Of Acute Myocardial Infarction In Egyptian Population, 11th National Conference of Biochemistry and Molecular Biology & Their Role in Development and Environment , 2014.
30 Mar - 1 Apr Ain Shams University - Cairo - Egypt

Journal 2014

Correcting the expression of miRNA 155 represses PP2AC and enhances the release of IL-2 in PBMCs of juvenile SLE patients

Lashine YA, Salah S, Aboelenin HR and AbdelAziz AI : Correcting the expression of miRNA 155 represses PP2AC and enhances the release of IL-2 in PBMCs of juvenile SLE patients, Lupus , 2014.

Journal 2014

Design and Synthesis of Novel Quinazoline Derivatives and Their Evaluation as PI3Ks Inhibitors

Omar Maged El-Said, Mostafa Mohamed Hamed, Stefan Laufer, Ashraf Hassan Abadi. : Design and Synthesis of Novel Quinazoline Derivatives and Their Evaluation as PI3Ks Inhibitors, Chem Pharm. Bull. (Tokyo). , 2014.
2014;62(12):1166-72.

Journal 2014

Design-of-Experiment Approach for HPLC Analysis of25-Hydroxy Vitamin D. A Comparative Assay with ELISA

Mohamed Abdulla Abu el Maaty, Rasha Sayed Hanafi, Hassan Y. Aboul-Enein, Mohamed Zakaria Gad : Design-of-Experiment Approach for HPLC Analysis of25-Hydroxy Vitamin D. A Comparative Assay with ELISA, Journal of Chromatographic Science , 2014.
DOI 10.1093/chromsci/bmu017, available online April 2014

Book Chapter 2014

Development of Agonists and Antagonists for Melatonin Receptors

Darius P. Zlotos : Development of Agonists and Antagonists for Melatonin Receptors, Melatonin and Melatonergic Drugs in Clinical Practice , 2014.
In Melatonin and Melatonergic Drugs in Clinical Practice, V. Srinivasan et al. (eds) , pp 97-116, Springer India, 2014

Conference 2014

Discovery of Novel Series of Tetrahydro-beta Carbolines Inducing Autophagic Cell Death in Human Metastatic Melanoma

Nermin S. Ahmed , Mohamed Elgendy , Stefan Laufer , Ashraf H. Abadi : Discovery of Novel Series of Tetrahydro-beta Carbolines Inducing Autophagic Cell Death in Human Metastatic Melanoma , Building International Networks for Enhancement of Research, Jordan , 2014.

Conference 2014

Drug Discovery using Chemical Libraries.

Ashraf H. Abadi. : Drug Discovery using Chemical Libraries. , Scientific Congress of teh Associations of Colleges of Pharmacy in the Arab World , 2014.
Cairo, Egypt. October 2014

Conference 2014

Dual Inhibitors of Epidermal Growth factor receptor kinase and the NF-?B pathway as potential anti-cancer drugs with enhanced efficacy.

5. Mostafa M. Hamed, Jennifer Hermann, Ashraf H. Abadi, Rolf W. Hartmann, Matthias Engel : Dual Inhibitors of Epidermal Growth factor receptor kinase and the NF-?B pathway as potential anti-cancer drugs with enhanced efficacy. , XXIII International Symposium on Medicinal Chemistry , 2014.
Lisbon, Portugal September 2014

Journal 2014

Effect of Polymorphisms in the NADSYN1/DHCR7 Locus (rs12785878 and rs1790349) on Plasma 25-Hydroxyvitamin D Levels and Coronary Artery Disease Incidence

Mohamed A. Abu el Maaty, Sally I. Hassanein, Hameis M. Sleem, Mohamed Z. Gad : Effect of Polymorphisms in the NADSYN1/DHCR7 Locus (rs12785878 and rs1790349) on Plasma 25-Hydroxyvitamin D Levels and Coronary Artery Disease Incidence, J Nutrigenet Nutrigenomics , 2014.
March 15, 2014, 6(6):327–335

Journal 2014

Enantiomeric Separation of underivatized amino acids: Predictability of chiral recognition on Ristocetin A chiral stationary phase

Hebattallah Wagdy, Rasha Hanafi. Rasha Elnashar, Hassan Abiulenein : Enantiomeric Separation of underivatized amino acids: Predictability of chiral recognition on Ristocetin A chiral stationary phase, Chirality , 2014.
26:132-135

Journal 2014

Enantiomeric Separation of Underivatized Amino Acids: Predictability of Chiral Recognition on Ristocetin A Chiral Stationary Phase

Hebatallah A. Wagdy, Rasha S. Hanafi, Rasha M. El-Nashar, Hassan Y. Aboul-Enein : Enantiomeric Separation of Underivatized Amino Acids: Predictability of Chiral Recognition on Ristocetin A Chiral Stationary Phase, Chirality , 2014.

Journal 2014

Evaluation of Plant Phenolic Metabolites as a Source of Alzheimer’s Drug Leads

Yara Hassaan,Heba Handoussa, Ahmed H. El-Khatib, MichaelW. Linscheid, Nesrine El Sayed and Nahla Ayoub : Evaluation of Plant Phenolic Metabolites as a Source of Alzheimer’s Drug Leads, BioMed Research International , 2014.

Journal 2014

Expression signature of microRNA-155 in genotype 4 HCV infection.

Riad SE, El Ekiaby NM, Mekky RY, Ahmed R, Mohey El Din MA, El Sayed M, Abouelkhair MM, Salah A, Zekri A, Esmat G, Abdelaziz AI : Expression signature of microRNA-155 in genotype 4 HCV infection. , BioMed. Rep , 2014.

Collection 2014

Glycine Receptors

2014 eLS Glycine Receptors Review.pdf Breitinger, H.-G. (2014) : Glycine Receptors, eLS - electronic Library of Science (Review Article) , 2014.
electronic Library of Science (eLS) invited Review. (eLS, 2014)

Journal 2014

In vivo protection against strychnine toxicity in mice by the glycine receptor agonist ivermectin

2014 IVM protects vs Strychnine iv.pdf Maher, A., Radwan, R., Breitinger, H.-G. (2014) : In vivo protection against strychnine toxicity in mice by the glycine receptor agonist ivermectin, BioMedRes International , 2014.
BioMedRes Intl. 2014, Article ID 640790. IF 2014 2.7

Conference 2014

Insights on Vitamin D’s Role in Cardiovascular Disease: Investigating the Association of 25-Hydroxyvitamin D with the Dimethylated Arginines

Mohamed A. Abu el Maaty, Sally I. hassanin, Rasha S. Hanafi and Mohamed Z Gad : Insights on Vitamin D’s Role in Cardiovascular Disease: Investigating the Association of 25-Hydroxyvitamin D with the Dimethylated Arginines, Vitamin D and Human Health: From the Gamete to the Grave , 2014.
London, Queen Mary, University of London , 23–25 April

Workshop 2014

Intellectual property and Antiviral Medications

Ashraf H. Abadi : Intellectual property and Antiviral Medications, Fraunhofer Workshop on Infection Biology and Aquaculture , 2014.
DAAD, Cairo, Egypt September 2014.

Journal 2014

Interplay between lipo-polysaccahride induced oxidative stress and amyloid beta deposition in Alzheimer’s disease and treatment with glycyrrhizin

Ragwa Mansour Abdelghany, Nadia Mohamed Sharaf, Nesrine Salah El Dine, Laila Gamal Mahran : Interplay between lipo-polysaccahride induced oxidative stress and amyloid beta deposition in Alzheimer’s disease and treatment with glycyrrhizin, Journal of Experimental and Applied Animal Science , 2014.

Journal 2014

Interplay between LPS induced oxidative stress and Amyloid beta deposition in Alzheimer’s disease and treatment with Glycyrrhizin

Ragwa Mansour, Nadia Sharaf, Nesrine Salah eldin, Laila Gamal Mahran : Interplay between LPS induced oxidative stress and Amyloid beta deposition in Alzheimer’s disease and treatment with Glycyrrhizin, Journal of Experimental and Applied Animal Sciences , 2014.

Journal 2014

Interplay of Vitamin D and Nitric Oxide in Post-Menopausal Knee Osteoarthritis

Mohamed A. Abu el Maaty, Rasha Hanafi, Samir El-Badawy, Mohamed Z. Gad : Interplay of Vitamin D and Nitric Oxide in Post-Menopausal Knee Osteoarthritis, Aging Clinical and Experimental Reserach , 2014.
26(4): 363-368. (August 2014)

Conference 2014

Investigating Polymorphisms in the NADSYN1/DHCR7 Locus (rs1790349 and rs12785878) as Novel Genetic Markers for Cardiovascular Disease.

Sally I. Hassanein, Mohamed A. Abu el Maaty, Hameis M. Sleem : Investigating Polymorphisms in the NADSYN1/DHCR7 Locus (rs1790349 and rs12785878) as Novel Genetic Markers for Cardiovascular Disease. , Vitamin D and Human Health: From the Gamete to the Grave , 2014.
London, Queen Mary, University of London , 23–25 April 2014

Journal 2014

Investigating the Cardio-Protective Abilities of Supplemental L-Arginine on Parameters of Endothelial Function in a Hypercholesterolemic Animal Model

Mohamed Z. GAD, Mohamed A. ABU EL MAATY, Shohda A. EL-MARAGHY, Atef T. FAHIM, Mohamed A. HAMDY : Investigating the Cardio-Protective Abilities of Supplemental L-Arginine on Parameters of Endothelial Function in a Hypercholesterolemic Animal Model, Journal of Nutritional Science and Vitaminology , 2014.
Vol. 60 No. 3, p.145-151

Conference 2014

Ion channels as mediators of cellular communication in health and disease – from structure-function analysis to the development of novel therapeutic strategies

Breitinger, H.-G. : Ion channels as mediators of cellular communication in health and disease – from structure-function analysis to the development of novel therapeutic strategies, ” BioChem Cairo, Medical Biochemistry and Molecular Biology International Meeting , 2014.
Lecture Presentation

Journal 2014

Is NKp44 (NCR2) a target for miR-181a? Lessons from NK cells and breast cancer patients

Mona Rady1, Carsten Watzl2, Maren Claus2, Ola Khorshid3, Laila Mahran1, Khaled Abou-Aisha1 : Is NKp44 (NCR2) a target for miR-181a? Lessons from NK cells and breast cancer patients, Cancer immunology and immunotherapy journal , 2014.

Conference 2014

Is There an Association Between CD14 C-260T Polymorphism and The Incidence of Acute Myocardial Infarction in Egyptian population ?

: Is There an Association Between CD14 C-260T Polymorphism and The Incidence of Acute Myocardial Infarction in Egyptian population ? , IFCC World Lab Istanbul , Turkey , 2014.

Conference 2014

Is there an association between CD14 C-260T polymorphism and the incidence of acute myocardial infarction in Egyptian population?

Ingy M. Hashad, Nancy M. Hossny, Mohamed F. Abdel Rahman, Sahar Abdel-Maksoud, Mohamed Z Gad : Is there an association between CD14 C-260T polymorphism and the incidence of acute myocardial infarction in Egyptian population?, IFCC WorldLab Istanbul 2014 , 2014.
22-26 June

Conference 2014

Mining ZINC Database to Discover Potential Phosphodiesterase 9 Inhibitors Using Structure-Based Drug Design Approach.

Ashraf H. Abadi, Engi Engi A. Hassan, Gary A. Piazza : Mining ZINC Database to Discover Potential Phosphodiesterase 9 Inhibitors Using Structure-Based Drug Design Approach. , International Scientific Committee. Humboldt-Kolleg / International Conference of Theory and Computation in Sciences and Bio-Sciences. , 2014.
Tlemcen, Algeria. November 2014

Conference 2014

Minocycline suppresses M1 microglia activation while enhancing phagocytosis of Aß fibrils

El-Shimy I.A, Heikal O. and Hamdi N : Minocycline suppresses M1 microglia activation while enhancing phagocytosis of Aß fibrils, 8th International Symposium on Neuroprotection Neurorepair 2014, The Magdeburg Meeting Series , 2014.

Conference 2014

miR-155 induces mTOR expression via activation of IGF-II/IGF-1R axis and inhibitionof IGFBP-3 in Hepatocellular Carcinoma

Hend M. El Tayebi, Amr A. Waly, Rana A. Youness, Mai A. Rahmon, Aya A. Bassiouni, Reem A. Assal, Karim A. Hosny, Gamal Esmat, Ahmed I. Abdelaziz : miR-155 induces mTOR expression via activation of IGF-II/IGF-1R axis and inhibitionof IGFBP-3 in Hepatocellular Carcinoma, American Association for Cancer Research (AACR), Philadelphia, USA. September 2014 , 2014.

Conference 2014

miR-155 induces mTOR expression via activation of IGF-II/IGF-1R axis and inhibitionof IGFBP-3 in Hepatocellular Carcinoma

Hend M. El Tayebi, Amr A. Waly, Rana A. Youness, Mai A. Rahmon, Aya A. Bassiouni, Reem A. Assal, Karim A. Hosny, Gamal Esmat, Ahmed I. Abdelaziz : miR-155 induces mTOR expression via activation of IGF-II/IGF-1R axis and inhibitionof IGFBP-3 in Hepatocellular Carcinoma, American Association for Cancer Research (AACR), Philadelphia, USA. , 2014.

Conference 2014

miR-155 induces mTOR expression via activation of IGF-II/IGF-1R axis and inhibitionof IGFBP-3 in Hepatocellular Carcinoma

Hend M. El Tayebi, Amr A. Waly, Rana A. Youness, Mai A. Rahmon, Aya A. Bassiouni, Reem A. Assal, Karim A. Hosny, Gamal Esmat, Ahmed I. Abdelaziz : miR-155 induces mTOR expression via activation of IGF-II/IGF-1R axis and inhibitionof IGFBP-3 in Hepatocellular Carcinoma , American Association for Cancer Research (AACR), Philadelphia, USA. , 2014.

Journal 2014

MiR-194 is a Hepatocyte Gate Keeper Hindering HCV Entry through Targeting CD81 Receptor

Mekky RY, El-Ekiaby NM, Hamza MT, El-Emam N, El-Sayed M, Esmat G and Abdelaziz AI : MiR-194 is a Hepatocyte Gate Keeper Hindering HCV Entry through Targeting CD81 Receptor, Journal of Infection , 2014.

Conference 2014

miR-194 is a Hepatocyte Gate Keeper Hindering HCV Entry through Targeting CD81 Receptor

Radwa Yehia Mekky, Nada Magdy El-Ekiaby, Mohammed Tarif Hamza, Mohammed EL-sayed, Gamal Esmat, Ahmed Ihab Abdelaziz : miR-194 is a Hepatocyte Gate Keeper Hindering HCV Entry through Targeting CD81 Receptor , Journal of Hepatology EASL– International Liver Congress 2014 (London,United Kingdom) , 2014.

Conference 2014

Molecular pathology of Hepatitis C – Characterization of the p7 ion channel protein as a potential therapeutic target

Breitinger, H.-G. Breitinger, U. : Molecular pathology of Hepatitis C – Characterization of the p7 ion channel protein as a potential therapeutic target, Biochemical Society Meeting, Ain Shams, Cairo, March 20, 2014 , 2014.
Invited Lecture

Journal 2014

MT1 and MT2 Melatonin Receptors: Ligands, Models, Oligomers, and Therapeutic Potential

Zlotos, D.P; Jockers, R.; Cecon, E.; Rivara, S.; Witt-Enderby, P.A. : MT1 and MT2 Melatonin Receptors: Ligands, Models, Oligomers, and Therapeutic Potential, Journal of Medicinal Chemistry , 2014.
2014, 57, 3161-3185

Journal 2014

N1-Linked Melatonin Dimers as Bivalent Ligands Targeting Dimeric Melatonin Receptors

Journe, A-S.; Habib, S.A.M; Dodda, B.R.; Morcos, M.N.F.; Sadek, M.S.; Tadros, S.A.A., Witt-Enderby, P.A.; Jockers, R.; Zlotos, D.P. : N1-Linked Melatonin Dimers as Bivalent Ligands Targeting Dimeric Melatonin Receptors , Medicinal Chemistry Communications, 2014, 5, 792-796. , 2014.

Journal 2014

Naphtahlene and 2,3-dihydrobenzo[b][1,4]dioxin Derivatives With Extended Side Chains as New Scaffolds of CB2 Selective Ligands.

Noha A. Osman, Amr H. Mahmoud, Christian D. Klein, Marco Allaràd, Vincenzo Di Marzod, Khaled M. Abouzid, Ashraf H. Abadi : Naphtahlene and 2,3-dihydrobenzo[b][1,4]dioxin Derivatives With Extended Side Chains as New Scaffolds of CB2 Selective Ligands., MedChem Comm , 2014.
5, 1571-157 (2014).

Conference 2014

Neuroprotective effect of thymoquinone against lipopolysaccharide induced Alzheimer in an animal model

Nadia M. Sharaf, Ragwa M. Abdelghany, Nesrine S. El Dine, Laila G. Mahran : Neuroprotective effect of thymoquinone against lipopolysaccharide induced Alzheimer in an animal model, 10th International Congress of the European Union Geriatric Medicine Society De Doelen, Rotterdam, The Netherlands , 2014.